Interpreting noninvasive prenatal paternity tests
نویسندگان
چکیده
منابع مشابه
Noninvasive Prenatal Paternity Testing (NIPAT) through Maternal Plasma DNA Sequencing: A Pilot Study
Short tandem repeats (STRs) and single nucleotide polymorphisms (SNPs) have been already used to perform noninvasive prenatal paternity testing from maternal plasma DNA. The frequently used technologies were PCR followed by capillary electrophoresis and SNP typing array, respectively. Here, we developed a noninvasive prenatal paternity testing (NIPAT) based on SNP typing with maternal plasma DN...
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For decades, noninvasive analysis of the fetal genotype has been the holy grail of the field of prenatal diagnosis. Noninvasive prenatal diagnosis (NIPD) would use a sample source other than amniocentesis or chorionic villus sampling. The focus has been primarily on the use of maternal blood samples, with less attention given to the possibility of recovering fetal cells from maternal cervical s...
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n engl j med 366;18 nejm.org may 3, 2012 1743 with vitamin B12, but both continue to have symptoms of peripheral neuropathy. There have been reports of false normal results for vitamin B12 levels generated by automated analyzers when the serum of patients with megaloblastic anemia is evaluated. The results have been attributed to the possibility that high levels of intrinsic factor–blocking ant...
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I became interested in the area of prenatal diagnosis when I was a medical student at Oxford. I had been following the impressive advances occurring in the prenatal diagnosis of the hemoglobinopathies through the pioneering work of Prof. Yuet Wai Kan at the University of California San Francisco (1 ) and Prof. David Weatherall at Oxford (2 ). I also had the good fortune of getting firsthand exp...
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ژورنال
عنوان ژورنال: Genetics in Medicine
سال: 2014
ISSN: 1098-3600,1530-0366
DOI: 10.1038/gim.2014.100